Assemble's current limitation with Edge is that we do not support multi-touch interactions with touchscreens.
Additionally, the popped out viewer is not available with Edge at this time. The option to use popped out viewer is enabled, although does not produce expected results.
We have some minor UI bugs, such as certain scroll bars not performing as expected, but can be worked around by using your mousewheel or keyboard arrows.
The request for complete Assemble functionality with Edge is in our development queue.